Molecules (Nov 2022)

Recent Development of Nano-Carbon Material in Pharmaceutical Application: A Review

  • Prastika K. Jiwanti,
  • Brasstira Y. Wardhana,
  • Laurencia G. Sutanto,
  • Diva Meisya Maulina Dewi,
  • Ilmanda Zalzabhila Danistya Putri,
  • Ilmi Nur Indira Savitri

DOI
https://doi.org/10.3390/molecules27217578
Journal volume & issue
Vol. 27, no. 21
p. 7578

Abstract

Read online

Carbon nanomaterials have attracted researchers in pharmaceutical applications due to their outstanding properties and flexible dimensional structures. Carbon nanomaterials (CNMs) have electrical properties, high thermal surface area, and high cellular internalization, making them suitable for drug and gene delivery, antioxidants, bioimaging, biosensing, and tissue engineering applications. There are various types of carbon nanomaterials including graphene, carbon nanotubes, fullerenes, nanodiamond, quantum dots and many more that have interesting applications in the future. The functionalization of the carbon nanomaterial surface could modify its chemical and physical properties, as well as improve drug loading capacity, biocompatibility, suppress immune response and have the ability to direct drug delivery to the targeted site. Carbon nanomaterials could also be fabricated into composites with proteins and drugs to reduce toxicity and increase effectiveness in the pharmaceutical field. Thus, carbon nanomaterials are very effective for applications in pharmaceutical or biomedical systems. This review will demonstrate the extraordinary properties of nanocarbon materials that can be used in pharmaceutical applications.

Keywords