INTESTINAL NEURONAL DYSPLASIA, TYPE B - A CASE REPORT

Journal of Evidence Based Medicine and Healthcare. 2015;2(15):2339 -2342 DOI 10.18410/jebmh/331

 

Journal Homepage

Journal Title: Journal of Evidence Based Medicine and Healthcare

ISSN: 2349-2562 (Print); 2349-2570 (Online)

Publisher: Level Up Business Center

Society/Institution: Level Up Business Center

LCC Subject Category: Medicine: Medicine (General): General works

Country of publisher: India

Language of fulltext: English

Full-text formats available: PDF

 

AUTHORS

Lakshmi Vasavi (H.)
Kiran Kumar (E. )

EDITORIAL INFORMATION

Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 8 weeks

 

Abstract | Full Text

Intestinal neuronal dysplasia (IND) is one of the conditions known to mimic Hirschsprung’s disease (HD) both clinically and radiologically, and clinically presents with intestinal obstruction in pediatric age group. Two types are described. 1 IND Type A is characterized by a malformation of the adrenergic nerve supply to the blood vessels and IND Type B, in which the submucosal plexus is involved. Giant ganglia are involved in Type B, and there is abnormal morphology of the nerve cell groups and nerve cell fibres. 2 In the present case, diagnosis was established mainly by biopsy and microscopic examination of H&E stained sections, which show increased ganglion cells both in number and size, and confirmed by Cathepsin D immunostaining.