Discovery of Potent Glucokinase and PPARγ Dual-Target Agonists through an Innovative Scheme for Regioselective Modification of Silybin

• Zhipeng Zhang,
• Yanqiu Meng,
• Zhan Wang,
• Yu Mei,
• Shite Gao,
• Yuejiao Wu,
• Shuxian Du

Affiliations

Zhipeng Zhang

Department of Pharmacy and Bioengineering, Shenyang University of Chemical Technology, Shenyang, Liaoning, China

Yanqiu Meng

Department of Pharmacy and Bioengineering, Shenyang University of Chemical Technology, Shenyang, Liaoning, China

Zhan Wang

Analysis and Testing Center, Shenyang University of Chemical Technology, Shenyang, Liaoning, China

Yu Mei

Department of Pharmacy and Bioengineering, Shenyang University of Chemical Technology, Shenyang, Liaoning, China

Shite Gao

Department of Pharmacy and Bioengineering, Shenyang University of Chemical Technology, Shenyang, Liaoning, China

Yuejiao Wu

Department of Pharmacy and Bioengineering, Shenyang University of Chemical Technology, Shenyang, Liaoning, China

Shuxian Du

Department of Pharmacy and Bioengineering, Shenyang University of Chemical Technology, Shenyang, Liaoning, China