Romanian Journal of Medical Practice (Mar 2018)
CARDIOVASCULAR DISEASE MANAGEMENT IN A PATIENT WITH CHRONIC KIDNEY DISEASE IN PRIMARY CARE
Abstract
Cardiovascular disease in patients with chronic renal disease (CKD) is commonly found in primary care. It is important to recognize chronic kidney disease, defined as abnormalities of kidney function or structure (markers of renal impairment) or eGFR of less than 60 ml / min / 1.73 m2 , presented for more than 3 months. Chronic kidney disease has an estimated prevalence of 8-11% worldwide. After the age of 40 years, there may be a physiological progressive reduction in eRFG (glomerular filtration rate) of 1 ml / min / year. Chronic kidney disease is an independent cardiovascular risk factor; low glomerular filtration rate (eGFR) is associated with increased mortality, multiple cardiovascular events and multiple hospitalizations. Cardiovascular risk assessment in patients should take into account the degree of renal function. Evaluation of renal function is based on eRFG and albuminuria or creatinine / albumin ratio. On the other hand, chronic kidney disease increases the risk of fatal and non-fatal cardiovascular events. Trying to identify and to control modifiable risk factors has beneficial effects on maintaining renal function and slowing down progression. The choice of medication and therapy should be made in accordance with the degree of impairment of renal function. General measures (smoking cessation, limitation of salt intake, aerobic exercise), good control of high blood pressure, optimal glycemic control, lipid lowering therapies, antiplatelet agents help to reduce the risk of cardiovascular events and at the same time, delay progression of function kidney˝.
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