СРАВНИТЕЛЬНЫЙ АНАЛИЗ УРОВНЯ ПРОВОСПАЛИТЕЛЬНЫХ ЦИТОКИНОВ У ПАЦИЕНТОВ С ХРОНИЧЕСКОЙ ОБ СТРУКТИВНОЙ БОЛЕЗНЬЮ ЛЕГКИХ в зависимости от стадии заболевания

Abstract

We examined 98 patients with chronic obstructive pulmonary disease (COPD) of varying severity in active phase of the fading. Levels of IL-8, γ-IF, TNF-α in sputum, bronchial washings and serum of patients with COPD were studied. Correlation between cytokine data with cytological structure of sputum and bronchial washings and C-reactive protein serum depending on the stage of disease was confirmed. Communication of smoking with activity of local and system inflammatory process was revealed.

Keywords

• chronic obstructive pulmonary disease
• inflammation
• cytokines