RITUXIMAB IN PEDIATRIC RHEUMATOLOGY

E.I. Alexeeva; R.V. Denisova; S.I. Valieva; T.M. Bzarova; A.O. Lisitsyn

Вопросы современной педиатрии (May 2010)

RITUXIMAB IN PEDIATRIC RHEUMATOLOGY

E.I. Alexeeva,
R.V. Denisova,
S.I. Valieva,
T.M. Bzarova,
A.O. Lisitsyn

Affiliations

E.I. Alexeeva: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
R.V. Denisova: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
S.I. Valieva: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
T.M. Bzarova: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow
A.O. Lisitsyn: Scientific Center of Children’s Health, Russian Academy of Medical Sciences, Moscow

Journal volume & issue: Vol. 9, no. 3
pp. 54 – 62

Abstract

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The article presents literature review on the role of B-lymphocytes in pathogenesis of rheumatologic diseases and on the administration of chimeric anti-CD20 monoclonal antibodies — rituximab — for treatment of systemic lupus erythematosus, systemic vasculitis, juvenile dermatomyositis, and juvenile arthritis in children. Results of studies showed that rituximab has good tolerability, efficacy and safety in children’s rheumatologic practice.Key words: children, B-lymphocytes, rituximab, treatment, depletion.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(3):54-62)

Published in Вопросы современной педиатрии

ISSN: 1682-5527 (Print); 1682-5535 (Online)
Publisher: "Paediatrician" Publishers LLC
Country of publisher: Russian Federation
LCC subjects: Medicine: Pediatrics
Website: https://vsp.spr-journal.ru

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