The predictive value of pan-immune inflammatory index for early recurrence of atrial fibrillation after cryoablation

Abstract

Abstract Objective The pan-immune inflammatory (PIV) index holds prognostic value for cardiovascular diseases. This study aimed to investigate the predictive value of the PIV index regarding recurrence of atrial fibrillation (AF) after cryoballoon ablation (CBA). Methods The study included 307 patients with AF. Four inflammatory markers, namely, the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune inflammation (SII) index, and PIV index, were used as indicators. COX regression analysis was conducted to evaluate the predictive value of AF recurrence after CBA. A receiver operating characteristic (ROC) curve was plotted, and the area under the curve (AUC) was calculated to evaluate the discriminative power of the indicators. Result The PIV index [94.9 (168.9,504.9) vs. 143.2 (98.2,210.6), P 260.7 had a higher recurrence rate at 1-year follow-up (P < 0.01). Subgroup analysis indicated that PIV had a predictive value in patients with different types of AF. Conclusion PIV index may be a potential biomarker for predicting relapse in patients with AF after CBA.

Keywords

• Pan-immune inflammatory index
• Systemic immune index
• Atrial fibrillation
• Cryoballoon ablation