Generation of an induced pluripotent stem cell lines HMSCASTi001-A from peripheral blood mononuclear cells of a 35-year-old healthy male

Zhanchi Zhang; Jingrui Liu; Jiamin Zhang; Xian Xian; Peipei Hao; Yingtong Zhai; Jingke Cheng; Fengming Yue; Feng Luan; Min Ma; Qian Ren

Stem Cell Research (Oct 2022)

Generation of an induced pluripotent stem cell lines HMSCASTi001-A from peripheral blood mononuclear cells of a 35-year-old healthy male

Zhanchi Zhang,
Jingrui Liu,
Jiamin Zhang,
Xian Xian,
Peipei Hao,
Yingtong Zhai,
Jingke Cheng,
Fengming Yue,
Feng Luan,
Min Ma,
Qian Ren

Affiliations

Zhanchi Zhang: Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, PR China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang 050017, PR China
Jingrui Liu: Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang 050017, PR China
Jiamin Zhang: Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, PR China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, PR China
Xian Xian: International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, PR China; Department of Pathogenic Biology, Hebei Medical University, Shijiazhuang 050017, PR China
Peipei Hao: Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, PR China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, PR China; Hebei Research Center for Stem Cell Medical Translational Engineering, Shijiazhuang 050017, PR China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang 050017, PR China
Yingtong Zhai: Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, PR China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, PR China
Jingke Cheng: Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, PR China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, PR China
Fengming Yue: International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, PR China; Hebei Research Center for Stem Cell Medical Translational Engineering, Shijiazhuang 050017, PR China; Department of Anatomy and Organ Technology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan
Feng Luan: Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang 050017, PR China
Min Ma: Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, PR China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang 050017, PR China
Qian Ren: Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, PR China; International Cooperation Laboratory of Stem Cell Research, Institute of Medical and Health Science, Hebei Medical University, Shijiazhuang 050017, PR China; Hebei Research Center for Stem Cell Medical Translational Engineering, Shijiazhuang 050017, PR China; Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang 050017, PR China; Corresponding author at: Department of Human Anatomy, Hebei Medical University, Shijiazhuang 050017, PR China.

Journal volume & issue: Vol. 64
p. 102908

Abstract

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Peripheral blood mononuclear cells derived from a 35-year-old healthy male were reprogrammed into induced pluripotent stem cells (iPSCs). The iPSCs maintained a normal karyotype, expressed various pluripotency stem cell markers, and showed potential of differentiating into three germ layers. This iPSCs could be differentiated into multiple cell subtypes for drug discovery and investigation of mechanisms.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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