Folia Medica
(Mar 2017)
Effects of the Novel High-affinity 5-HT(1B/1D)-receptor Ligand Frovatriptan on the Rat Carotid Artery
Saracheva Kremena E.,
Prissadova Natalia A.,
Turiiski Valentin I.,
Slavchev Valeri I.,
Krastev Atanas D.,
Getova Damianka P.
Affiliations
Saracheva Kremena E.
Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria Bulgaria
Prissadova Natalia A.
Department of Medical Physics and Biophysics, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria
Turiiski Valentin I.
Department of Medical Physics and Biophysics, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria
Slavchev Valeri I.
Department of Medical Physics and Biophysics, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria
Krastev Atanas D.
Department of Medical Physics and Biophysics, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria
Getova Damianka P.
Laboratory of Neuropharmacology, Technological Center for Emergency Medicine (TCEMED), Plovdiv, Bulgaria
DOI
https://doi.org/10.1515/folmed-2017-0006
Journal volume & issue
Vol. 59,
no. 1
Abstract
Read online
Background: In blood vessels 5-HT stimulates sympathetic nerves, the endothelium and vascular smooth muscle cells. Triptans are specific anti-migraine drugs and they activate the serotoninergic 5HT1b/d receptors causing vasoconstriction of the cerebral vessels.
Keywords
Published in Folia Medica
ISSN
0204-8043 (Print)
1314-2143 (Online)
Publisher
Pensoft Publishers
Country of publisher
Bulgaria
LCC subjects
Medicine
Website
https://foliamedica.bg
About the journal
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