Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
Muhammad Imran,
Fereshteh Ghorat,
Iahtisham Ul-Haq,
Habib Ur-Rehman,
Farhan Aslam,
Mojtaba Heydari,
Mohammad Ali Shariati,
Eleonora Okuskhanova,
Zhanibek Yessimbekov,
Muthu Thiruvengadam,
Mohammad Hashem Hashempur,
Maksim Rebezov
Affiliations
Muhammad Imran
University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore 54000, Pakistan
Fereshteh Ghorat
Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar 9617913112, Iran
Iahtisham Ul-Haq
Department of Diet and Nutritional Sciences, Faculty of Health and Allied Sciences, Imperial College of Business Studies, Lahore 53720, Pakistan
Habib Ur-Rehman
Department of Clinical Nutrition, NUR International University, Lahore 54000, Pakistan
Farhan Aslam
Department of Food Science and Human Nutrition, University of Veterinary and Animal Sciences, Lahore Syed Abdul Qadir Jillani (Out Fall) Road, Lahore 54000, Pakistan
Mojtaba Heydari
Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz 7134845794, Iran
Mohammad Ali Shariati
Department of Technology of Food Products, K.G. Razumovsky Moscow State University of Technologies and Management (the First Cossack University), 109004 Moscow, Russia
Eleonora Okuskhanova
Food Science and Technology Department, Shakarim State University of Semey, Semey 071412, Kazakhstan
Zhanibek Yessimbekov
Food Science and Technology Department, Shakarim State University of Semey, Semey 071412, Kazakhstan
Muthu Thiruvengadam
Department of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul 05029, Korea
Mohammad Hashem Hashempur
Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa 7461686688, Iran
Maksim Rebezov
V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, Moscow 109029, Russia
Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant and a non-pro-vitamin A carotenoid. Lycopene has been found to be efficient in ameliorating cancer insurgences, diabetes mellitus, cardiac complications, oxidative stress-mediated malfunctions, inflammatory events, skin and bone diseases, hepatic, neural and reproductive disorders. This review summarizes information regarding its sources and uses amongst different societies, its biochemistry aspects, and the potential utilization of lycopene and possible mechanisms involved in alleviating the abovementioned disorders. Furthermore, future directions with the possible use of this nutraceutical against lifestyle-related disorders are emphasized. Its protective effects against recommended doses of toxic agents and toxicity and safety are also discussed.
