Antioxidant activity and sun screening effects of Bacterial melanin

Abstract

The present work was delineated to formulate and evaluate antioxidant and photoprotective properties of melanin produced by Pseudomonas mosseliistrain STSGRDS1 against the purchased fungal melanin STSGRDM1 as standard. Initially, antioxidant assay was examined for the isolated bacterial melanin STSGRDS1 against the standard melanin STSGRDM1 that already have substantiated to have the antioxidant ability by DPPH and ABTS, following with the detailed screening of radical scavenging activity were performed which includes the valuation of peroxides, hydroxyl radicals, reduction potential, and phosphomolybdenum method. This report depicts the antioxidant potential of the extracted melanin that could be further used as a potent antioxidant on scientific basis, as the percentage of free radical scavenging increased with increasing concentration of melanin. The study also signifies that bacterial melanin formulated creams had the potency to protect against ultraviolet (UV) rays with sun protection factor (SPF) enhancement ranging from 1.95 to 26.06 and transmission spectroscopy revealed that the formulations have satisfied protection against UV A and UV B rays with good average UV A protection factor indicating sunscreen activity of the pigment. As a result, the isolated bacterial strain has immense photoprotection potential and radical scavenging activity that can be resorted to in cosmetic formulations, UVprotection devices, etc.

Keywords

• melanin
• pseudomonas sp
• antioxidant
• spf
• transmission spectroscopy