Nature Communications (Feb 2022)

Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer

  • Zaoqu Liu,
  • Long Liu,
  • Siyuan Weng,
  • Chunguang Guo,
  • Qin Dang,
  • Hui Xu,
  • Libo Wang,
  • Taoyuan Lu,
  • Yuyuan Zhang,
  • Zhenqiang Sun,
  • Xinwei Han

DOI
https://doi.org/10.1038/s41467-022-28421-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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Identification of long non-coding RNA (lncRNA) signatures could be used to improve cancer clinical outcome. Here the authors developed a machine learning-based integrative procedure to construct a consensus immune-related lncRNA signature to predict prognosis, recurrence and treatment benefits in colorectal cancer.