Role of adding T2 mapping sequence to the routine MR imaging protocol in the assessment of articular knee cartilage in osteoarthritis

Abstract

Abstract Background This work aims at elucidating the role of adding complementary T2 mapping to the routine 1.5 Tesla MRI protocol in the articular knee cartilage assessment for early detection of osteoarthritis, and also, comparing the articular cartilage thickness and T2 relaxation times between the case and control groups regarding knee compartments affection. Results Both sensitivities and specificities were 73.3% and 100%, respectively, for the standard MR protocol alone and 96.7% and 90% after adding the T2 mapping to the standard MR protocol that leads to significant sensitivity improvement. A comparison between patients and controls as regards T2 values showed a highly statistically significant difference (independent T test, p <0.001). Conclusion A combination of both morphological and T2 mapping MRI, together with clinical evaluation represents a desirable multimodal approach to the diagnosis of osteoarthritis. In the early detection of osteoarthritis, adding T2 mapping sequence to the standard MR protocol at 1.5 Tesla improved sensitivity from 73.3 to 96.7%.

Keywords

• T2 mapping
• Articular knee cartilage
• Osteoarthritis
• Knee compartments
• And cartilage thickness