Zollinger-Ellison syndrome: a case report

Abstract

Background: Zollinger-Ellison syndrome is the consequence of excessive and autonomous secretion of gastrin from gastrinoma cells. The disease is exceptionally rare and characterized by severe and treatment-resistant peptic disease that can become life-threatening for a patient. In most cases, gastrinoma is malignant. A case of 44-year patient is presented.Conclusions: We present clinical manifestations, laboratory diagnostic tests, modalities of tumor localization and forms of treatment that are clinically relevant in a patient, suspected of having this rare disease. Pathohistologically, our patient’s tumor was identified as a carcinoid with minor gastrinoma fraction.

Keywords

• Zollinger-Ellison syndrome
• gastrinoma
• diagnostics
• differential diagnosis
• treatment