Van Tıp Dergisi (Jul 2018)
Bilateral Renal Vein Thrombosis with Inutero Onset in a Preterm Newborn: A Case Report
Abstract
Reno-vascular thromboembolic complications are observed more frequently in newborn period due to decreasing renal blood build-up, low natural anticoagulant levels, and increased blood viscosity and hyperosmolality. Among the thrombosis cases that are irrelevant with catheter, Renal Vein Thrombosis (RVT) has the highest prevalence with 16-20%. Perinatal asphyxia history, maternal diabetes mellitus, prematurity, dehydration, cyanotic congenital heart disease, infection and genetic defects that give rise to predisposition to thrombosis (Protein C, protein S and antithrombin deficiency, factor V Leiden mutation, prothrombin and methylene tetra hydro folate reductase gene mutations) are among the risk factors. There are anticoagulant and fibrinolytic treatments during the management. Widespread kidney dysfunction comes to the forefront among the long-term complications. In the present study, a bilateral Renal Vein Thrombosis case that is rare in the literature with the emergence time and form and relevant risk factors is presented.
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