A time-resolved multi-omic atlas of the developing mouse stomach

Xianju Li; Chunchao Zhang; Tongqing Gong; Xiaotian Ni; Jin’e Li; Dongdong Zhan; Mingwei Liu; Lei Song; Chen Ding; Jianming Xu; Bei Zhen; Yi Wang; Jun Qin

doi:10.1038/s41467-018-07463-9

Nature Communications (Nov 2018)

A time-resolved multi-omic atlas of the developing mouse stomach

Xianju Li,
Chunchao Zhang,
Tongqing Gong,
Xiaotian Ni,
Jin’e Li,
Dongdong Zhan,
Mingwei Liu,
Lei Song,
Chen Ding,
Jianming Xu,
Bei Zhen,
Yi Wang,
Jun Qin

Affiliations

Xianju Li: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Chunchao Zhang: Alkek Center for Molecular Discovery, Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Department of Molecular and Cellular Biology, Baylor College of Medicine
Tongqing Gong: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Xiaotian Ni: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Jin’e Li: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Dongdong Zhan: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Mingwei Liu: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Lei Song: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Chen Ding: State Key Laboratory of Genetic Engineering, Human Phenome Institute, Institutes of Biomedical Sciences, and School of Life Sciences, Zhongshan Hospital, Fudan University
Jianming Xu: Department of Gastrointestinal Oncology, Affiliated Hospital Cancer Center, Academy of Military Medical Sciences
Bei Zhen: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Yi Wang: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)
Jun Qin: State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (The PHOENIX Center, Beijing)

DOI: https://doi.org/10.1038/s41467-018-07463-9
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 13

Abstract

Read online

The mammalian stomach is a complex organ with diverse roles in health and disease. Here, the authors integrate proteomics and transcriptomics to analyze the mouse stomach at 15 time points during development, providing molecular level insights into system-wide developmental changes.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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