Case Reports in Dentistry (Jan 2023)

Multiple Cemento-Ossifying Fibroma: A Sign of Hyperparathyroidism-Jaw Tumour Syndrome

  • Nurul Inaas Mahamad Apandi,
  • Nor Nazaliza Basri,
  • Ajura Abdul Jalil,
  • Md Arad Jelon

DOI
https://doi.org/10.1155/2023/4664619
Journal volume & issue
Vol. 2023

Abstract

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Hyperparathyroidism-jaw tumour (HPT-JT) syndrome is a rare autosomal dominant disease. It is caused by a gene mutation of the tumour suppressor gene CDC73 that encodes for parafibromin. This syndrome predisposes to a triad occurrence of multiple maxillary or mandibular cemento-ossifying fibroma, parathyroid adenoma or carcinoma, and renal and uterine tumours. In this study, we report a case of HPT-JT occurring in a 30-year-old male patient.