Acta Medica Martiniana (Aug 2024)

Calculated PRA and PIRCHE Algorithm in Kidney Transplant Recipients

  • Ivana Dedinska,
  • Andrej Ceres,
  • Martina Schniederova,
  • Karol Granak,
  • Matej Vnucak,
  • Monika Beliancinova,
  • Patricia Kleinova,
  • Timea Blichova,
  • Milos Jesenak

DOI
https://doi.org/10.2478/acm-2024-0008
Journal volume & issue
Vol. 24, no. 2
pp. 55 – 65

Abstract

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Calculated PRA testing in kidney transplantation has revolutionized the field by enabling a more accurate assessment of compatibility and risk prediction for AMR. On the other hand, The PIRCHE algorithm aims to identify the potentially immunogenic human leukocyte antigens (HLA) epitopes on the donor graft that are recognized by the recipient's HLA antibodies.

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