Nature Communications (Apr 2022)
Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions
- Dheeraj S. Roy,
- Young-Gyun Park,
- Minyoung E. Kim,
- Ying Zhang,
- Sachie K. Ogawa,
- Nicholas DiNapoli,
- Xinyi Gu,
- Jae H. Cho,
- Heejin Choi,
- Lee Kamentsky,
- Jared Martin,
- Olivia Mosto,
- Tomomi Aida,
- Kwanghun Chung,
- Susumu Tonegawa
Affiliations
- Dheeraj S. Roy
- RIKEN-MIT Laboratory for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Young-Gyun Park
- Institute for Medical Engineering and Science, Picower Institute for Learning and Memory, Department of Chemical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Minyoung E. Kim
- Institute for Medical Engineering and Science, Picower Institute for Learning and Memory, Department of Chemical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Ying Zhang
- McGovern Institute for Brain Research, Massachusetts Institute of Technology
- Sachie K. Ogawa
- RIKEN-MIT Laboratory for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Nicholas DiNapoli
- Institute for Medical Engineering and Science, Picower Institute for Learning and Memory, Department of Chemical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Xinyi Gu
- Institute for Medical Engineering and Science, Picower Institute for Learning and Memory, Department of Chemical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Jae H. Cho
- Institute for Medical Engineering and Science, Picower Institute for Learning and Memory, Department of Chemical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Heejin Choi
- Institute for Medical Engineering and Science, Picower Institute for Learning and Memory, Department of Chemical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Lee Kamentsky
- Institute for Medical Engineering and Science, Picower Institute for Learning and Memory, Department of Chemical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Jared Martin
- RIKEN-MIT Laboratory for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- Olivia Mosto
- McGovern Institute for Brain Research, Massachusetts Institute of Technology
- Tomomi Aida
- McGovern Institute for Brain Research, Massachusetts Institute of Technology
- Kwanghun Chung
- Broad Institute of MIT and Harvard
- Susumu Tonegawa
- RIKEN-MIT Laboratory for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology
- DOI
- https://doi.org/10.1038/s41467-022-29384-4
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 16
Abstract
Where memories are located in our brains is not well understood. In this paper, the authors demonstrate that memories are spread out throughout multiple brain regions.
