Emerging Infectious Diseases (Apr 2024)

Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021–2022

  • Timothy J. Doyle,
  • Megan Gumke,
  • Danielle Stanek,
  • Joshua Moore,
  • Brian Buck,
  • Timothy Locksmith,
  • Kelly Tomson,
  • Sarah Schmedes,
  • George Churchwell,
  • Shan Justin Hubsmith,
  • Baskar Krishnamoorthy,
  • Karalee Poschman,
  • Brandi Danforth,
  • Daniel Chacreton

DOI
https://doi.org/10.3201/eid3004.231392
Journal volume & issue
Vol. 30, no. 4
pp. 634 – 643

Abstract

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In 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genotype IA. The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. The mpox outbreak in Florida (2,845 cases) was part of a global epidemic. The hepatitis A and IMD outbreaks were concentrated in Central Florida and peaked during March–­June, whereas mpox cases were more heavily concentrated in South Florida and had peak incidence in August. HIV infection was more common (52%) among mpox cases than among hepatitis A (21%) or IMD (34%) cases. Where feasible, vaccination against hepatitis A, meningococcal disease, and mpox should be encouraged among at-risk groups and offered along with program services that target those groups.

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