Nature Communications (Apr 2023)

Distributed processing for value-based choice by prelimbic circuits targeting anterior-posterior dorsal striatal subregions in male mice

  • Kyuhyun Choi,
  • Eugenio Piasini,
  • Edgar Díaz-Hernández,
  • Luigim Vargas Cifuentes,
  • Nathan T. Henderson,
  • Elizabeth N. Holly,
  • Manivannan Subramaniyan,
  • Charles R. Gerfen,
  • Marc V. Fuccillo

DOI
https://doi.org/10.1038/s41467-023-36795-4
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 19

Abstract

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The prelimbic region of the prefrontal cortex is involved in goal-directed action. Here the authors investigate the function of the prelimbic pathways projecting along the anterior posterior striatal axis in value based decision making in male mice.