Emerging Infectious Diseases (Mar 2019)

Longitudinal Outbreak of Multidrug-Resistant Tuberculosis in a Hospital Setting, Serbia

  • Irena Arandjelović,
  • Matthias Merker,
  • Elvira Richter,
  • Thomas A. Kohl,
  • Branislava Savić,
  • Ivan Soldatović,
  • Thierry Wirth,
  • Dragana Vuković,
  • Stefan Niemann

DOI
https://doi.org/10.3201/eid2503.181220
Journal volume & issue
Vol. 25, no. 3
pp. 555 – 558

Abstract

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A retrospective population-based molecular epidemiologic study of multidrug-resistant Mycobacterium tuberculosis complex strains in Serbia (2008–2014) revealed an outbreak of TUR genotype strains in a psychiatric hospital starting around 1990. Drug unavailability, poor infection control, and schizophrenia likely fueled acquisition of additional resistance and bacterial fitness–related mutations over 2 decades.

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