The author presents an integral vision of a human being as the foundation for understanding vocation and respect for life. It emphasizes the truths: man as a body and spirit being; the dignity and worth of every person created in the image and likeness of God; the vocation to love, i.e. the ability to give oneself as a gift. As a source for reflection, it is the light of God’s truth found in the Holy Scriptures and in the Catechism of the Catholic Church. The author shows the socio-cultural problems related to the lack of respect for human values that are taking place today. It presents the necessity of catechesis in social life, which is to respond with faith to human existence. It presents the problems posed by the world and the response of catechetical content to particular threats.