Frontiers in Human Neuroscience (Mar 2020)
Proceedings of the Seventh Annual Deep Brain Stimulation Think Tank: Advances in Neurophysiology, Adaptive DBS, Virtual Reality, Neuroethics and Technology
- Adolfo Ramirez-Zamora,
- James Giordano,
- Aysegul Gunduz,
- Aysegul Gunduz,
- Jose Alcantara,
- Jose Alcantara,
- Jackson N. Cagle,
- Jackson N. Cagle,
- Stephanie Cernera,
- Stephanie Cernera,
- Parker Difuntorum,
- Parker Difuntorum,
- Robert S. Eisinger,
- Robert S. Eisinger,
- Julieth Gomez,
- Julieth Gomez,
- Sarah Long,
- Sarah Long,
- Brandon Parks,
- Brandon Parks,
- Joshua K. Wong,
- Shannon Chiu,
- Bhavana Patel,
- Warren M. Grill,
- Harrison C. Walker,
- Harrison C. Walker,
- Simon J. Little,
- Ro’ee Gilron,
- Gerd Tinkhauser,
- Gerd Tinkhauser,
- Wesley Thevathasan,
- Wesley Thevathasan,
- Wesley Thevathasan,
- Nicholas C. Sinclair,
- Nicholas C. Sinclair,
- Andres M. Lozano,
- Thomas Foltynie,
- Alfonso Fasano,
- Alfonso Fasano,
- Sameer A. Sheth,
- Katherine Scangos,
- Terence D. Sanger,
- Jonathan Miller,
- Audrey C. Brumback,
- Priya Rajasethupathy,
- Priya Rajasethupathy,
- Cameron McIntyre,
- Leslie Schlachter,
- Nanthia Suthana,
- Cynthia Kubu,
- Lauren R. Sankary,
- Karen Herrera-Ferrá,
- Steven Goetz,
- Binith Cheeran,
- G. Karl Steinke,
- Christopher Hess,
- Leonardo Almeida,
- Wissam Deeb,
- Kelly D. Foote,
- Michael S. Okun
Affiliations
- Adolfo Ramirez-Zamora
- Department of Neurology, Norman Fixel Institute for Neurological Diseases, Program for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- James Giordano
- Departments of Neurology and Biochemistry, and Neuroethics Studies Program—Pellegrino Center for Clinical Bioethics, Georgetown University Medical Center, Washington, DC, United States
- Aysegul Gunduz
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Aysegul Gunduz
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Jose Alcantara
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Jose Alcantara
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Jackson N. Cagle
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Jackson N. Cagle
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Stephanie Cernera
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Stephanie Cernera
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Parker Difuntorum
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Parker Difuntorum
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Robert S. Eisinger
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Robert S. Eisinger
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Julieth Gomez
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Julieth Gomez
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Sarah Long
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Sarah Long
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Brandon Parks
- J. Crayton Pruitt Family Department of Biomedical Engineering, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Brandon Parks
- Department of Neurosurgery, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Joshua K. Wong
- Department of Neurology, Norman Fixel Institute for Neurological Diseases, Program for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Shannon Chiu
- Department of Neurology, Norman Fixel Institute for Neurological Diseases, Program for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Bhavana Patel
- Department of Neurology, Norman Fixel Institute for Neurological Diseases, Program for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Warren M. Grill
- Department of Biomedical Engineering, Duke University, Durham, NC, United States
- Harrison C. Walker
- Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, United States
- Harrison C. Walker
- Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL, United States
- Simon J. Little
- Department of Neurology, University of California, San Francisco, San Francisco, CA, United States
- Ro’ee Gilron
- Graduate Program in Neuroscience, Department of Neurological Surgery, Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, United States
- Gerd Tinkhauser
- 0Department of Neurology, Bern University Hospital and the University of Bern, Bern, Switzerland
- Gerd Tinkhauser
- 1Medical Research Council Brain Network Dynamics Unit, University of Oxford, Oxford, United Kingdom
- Wesley Thevathasan
- 2Department of Neurology, The Royal Melbourne and Austin Hospitals, University of Melbourne, Melbourne, VIC, Australia
- Wesley Thevathasan
- 3Medical Bionics Department, University of Melbourne, East Melbourne, VIC, Australia
- Wesley Thevathasan
- 4Bionics Institute, East Melbourne, VIC, Australia
- Nicholas C. Sinclair
- 3Medical Bionics Department, University of Melbourne, East Melbourne, VIC, Australia
- Nicholas C. Sinclair
- 4Bionics Institute, East Melbourne, VIC, Australia
- Andres M. Lozano
- 5Department of Surgery, Division of Neurosurgery, University of Toronto, Toronto, ON, Canada
- Thomas Foltynie
- 6Institute of Neurology, University College London, London, United Kingdom
- Alfonso Fasano
- 7Edmond J. Safra Program in Parkinson’s Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, ON, Canada
- Alfonso Fasano
- 8Division of Neurology, University of Toronto, Krembil Brain Institute, Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada
- Sameer A. Sheth
- 9Department of Neurological Surgery, Baylor College of Medicine, Houston, TX, United States
- Katherine Scangos
- 0Department of Psychiatry, University of California, San Francisco, San Francisco, CA, United States
- Terence D. Sanger
- 1Department of Biomedical Engineering, Neurology, Biokinesiology, University of Southern California, Los Angeles, CA, United States
- Jonathan Miller
- 2Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, United States
- Audrey C. Brumback
- 3Departments of Neurology and Pediatrics at Dell Medical School and the Center for Learning and Memory, University of Texas at Austin, Austin, TX, United States
- Priya Rajasethupathy
- 4Laboratory for Neural Dynamics and Cognition, Rockefeller University, New York, NY, United States
- Priya Rajasethupathy
- 5Department of Bioengineering, Stanford University, Stanford, CA, United States
- Cameron McIntyre
- 6Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States
- Leslie Schlachter
- 7Department of Neurosurgery, Mount Sinai Health System, New York, NY, United States
- Nanthia Suthana
- 8Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States
- Cynthia Kubu
- 9Department of Neurology, Cleveland Clinic, Cleveland, OH, United States
- Lauren R. Sankary
- 0Center for Bioethics, Cleveland Clinic, Cleveland, OH, United States
- Karen Herrera-Ferrá
- 1Asociación Mexicana de Neuroética, Mexico City, Mexico
- Steven Goetz
- 2Medtronic Neuromodulation, Minneapolis, MN, United States
- Binith Cheeran
- 3Neuromodulation Division, Abbott, Plano, TX, United States
- G. Karl Steinke
- 4Boston Scientific Neuromodulation, Valencia, CA, United States
- Christopher Hess
- Department of Neurology, Norman Fixel Institute for Neurological Diseases, Program for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Leonardo Almeida
- Department of Neurology, Norman Fixel Institute for Neurological Diseases, Program for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Wissam Deeb
- Department of Neurology, Norman Fixel Institute for Neurological Diseases, Program for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Kelly D. Foote
- 5Department of Neurosurgery, Norman Fixel Institute for Neurological Diseases, Center for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- Michael S. Okun
- Department of Neurology, Norman Fixel Institute for Neurological Diseases, Program for Movement Disorders and Neurorestoration, University of Florida, Gainesville, FL, United States
- DOI
- https://doi.org/10.3389/fnhum.2020.00054
- Journal volume & issue
-
Vol. 14
Abstract
The Seventh Annual Deep Brain Stimulation (DBS) Think Tank held on September 8th of 2019 addressed the most current: (1) use and utility of complex neurophysiological signals for development of adaptive neurostimulation to improve clinical outcomes; (2) Advancements in recent neuromodulation techniques to treat neuropsychiatric disorders; (3) New developments in optogenetics and DBS; (4) The use of augmented Virtual reality (VR) and neuromodulation; (5) commercially available technologies; and (6) ethical issues arising in and from research and use of DBS. These advances serve as both “markers of progress” and challenges and opportunities for ongoing address, engagement, and deliberation as we move to improve the functional capabilities and translational value of DBS. It is in this light that these proceedings are presented to inform the field and initiate ongoing discourse. As consistent with the intent, and spirit of this, and prior DBS Think Tanks, the overarching goal is to continue to develop multidisciplinary collaborations to rapidly advance the field and ultimately improve patient outcomes.
Keywords
- deep brain stimulation
- stereoelectroencephalography
- depression
- Parkinson’s disease
- tremor
- optogenetics
