Nature Communications (Sep 2020)

In vivo localization of chronically implanted electrodes and optic fibers in mice

  • Bálint Király,
  • Diána Balázsfi,
  • Ildikó Horváth,
  • Nicola Solari,
  • Katalin Sviatkó,
  • Katalin Lengyel,
  • Eszter Birtalan,
  • Magor Babos,
  • Gergő Bagaméry,
  • Domokos Máthé,
  • Krisztián Szigeti,
  • Balázs Hangya

DOI
https://doi.org/10.1038/s41467-020-18472-y
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 17

Abstract

Read online

Király et al. propose a method combining micro-CT and MRI imaging to precisely localize electrodes and optic fibers in the mouse brain in vivo. This allows assessing the success of targeting after surgery, depth adjustment of movable probes and identifying systematic errors in the surgical process.