فیزیولوژی ورزش و فعالیت بدنی (Aug 2018)

The effect of endurance training and iron supplementation on some cellular respiration factors in rats

  • Mohammad Ali Samavati Shari,
  • Aliasghar Ravasi,
  • Mohammad Reza Kordi,
  • Bagher Minaie,
  • Siavoshy Hojjatollah

DOI
https://doi.org/10.48308/joeppa.2018.98909
Journal volume & issue
Vol. 11, no. 1
pp. 13 – 28

Abstract

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Purpose: Iron plays an important role in oxygen transfer, mitochondrial respiratory chain enzymes, andoxidative phosphorylation; therefore, the reduction of iron can have a negative effect on the oxidativeperformance of athletes. The aim of study was investigate the effect of endurance exercise programs andiron supplementation on some cellular respiration factors in rats.Methods: Forty male wistar-rats were divided into four groups. experimental Group I, do endurance exerciseprograms on treadmill in during 12 weeks (intensity 32 m.min-1, 60 minutes in every session, and 5 sessionsin a week) (T). Experimental group II do same exercise program, but intake daily 800 micrograms ironsupplementary (Ferrous-Sulphate) (Ti). The control group C was without exercise (sedentary) (S), andexperimental group III, did not do any exercise, but received an 800 microgram daily iron supplement (Si).After 12 weeks, their blood and muscle tissue samples were analyses. Data were analyzed using one wayANOVA and Kruskal-Wallis Test (P<0.05).Results: Blood ferritin concentration only in the experimental group I and absolute weight of soleus muscleand cytochrome C oxidase only in the experimental group II than other groups was statistically significant(p<0.05). Also, muscle hypertrophy, capillary density, and mitochondrial density in the experimental groups Iand II compared with the control group and experimental group III were significantly different (p<0.05); But,this differences between both experimental groups I and II were not significant. Despite, body mass, relativeweight of soleus muscle, and maximum oxygen consumption in the Experimental groups compared with thecontrol group were significantly different and these differences between the experimental groups also weresignificant (p<0.05).Conclusions: It seems that iron supplementations combined with exercises maybe improve some markers ofcellular respiration, hypertrophy, and aerobic capacity; Despite, these improvements probably do not occurin detraining.

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