2-Amino-4-(4-fluorophenyl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile

Abstract

The title compound, C22H14FN3, was prepared by a one-pot condensation using malononitrile, an aromatic aldehyde, a methyl ketone and ammonium acetate as reactants under microwave irradiation. The pyridine ring is twisted with respect to the benzene ring and the naphthalene ring system, making dihedral angles of 41.9 (1) and 45.2 (1)°, respectively. In the crystal, molecules are connected via intermolecular N—H...N and C—H...F hydrogen bonds, forming a three-dimensional network.