325 Armored STEAP2 CAR-T (AZD0754) alone and in combination with enzalutamide demonstrates anti-tumor activity across a range of STEAP2 expressing prostate cancer PDX models

• Mark Cobbold,
• Gordon Moody,
• Kelly McGlinchey,
• Emily Bosco,
• Peter Zanvit,
• Christine Fazenbaker,
• Weichuan Luo,
• Jessica Pezold,
• Clare Hoover

Affiliations

Mark Cobbold

Aff293 grid.32224.350000000403869924Massachusetts General Hospital Cancer Center Boston MA USA

Gordon Moody

1AstraZeneca, Gaithersburg, MD, USA

Kelly McGlinchey

Aff3 grid.418152.bDepartment of OncologyMedImmune One Medimmune Way 20878 Gaithersburg MD USA

Emily Bosco

1AstraZeneca, Gaithersburg, MD, USA

Peter Zanvit

1AstraZeneca, Gaithersburg, MD, USA

Christine Fazenbaker

1AstraZeneca, Gaithersburg, MD, USA

Weichuan Luo

1AstraZeneca, Gaithersburg, MD, USA

Jessica Pezold

1AstraZeneca, Gaithersburg, MD, USA

Clare Hoover

2AstraZeneca, Cambridge, UK