The Proceedings of the Nigerian Academy of Science (Jul 2024)

Seroprevalence of Dengue and Hepatitis B infections among young adults attending a secondary health care facility at Olabisi Onabanjo University, Ogun State, Nigeria

  • Hafeez A. Adekola,
  • Georgia C. Agu,
  • Festus A. Odeyemi,
  • Haneefat O. Egberongbe,
  • Ismail B. Onajobi,
  • Wahab A. Kareem,
  • Oyesanya O. Adejonwo

DOI
https://doi.org/10.57046/DOTR8940
Journal volume & issue
Vol. 17, no. 1
pp. 95 – 102

Abstract

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Hepatitis B and Dengue virus infections carry significant public health implications due to their potential to cause illness and death. This study focused on examining the prevalence of these infections among young adults seeking care at a secondary health facility at Olabisi Onabanjo University. Ninety samples obtained from study participants underwent screening using Enzyme-linked Immunosorbent Assay (ELISA) for both HBsAg and Dengue IgM. The participants, predominantly female, were aged between 15 and 30 years. The analysis revealed a 13.3% prevalence of Dengue IgM, a 4.5% prevalence of HBsAg, and a 4.4% prevalence for both infections. Regarding age distribution, the highest prevalence occurred among participants aged 15-20 years for both single infections and the co-occurrence of Hepatitis B and Dengue viral infections. Examining gender distribution, female participants exhibited higher seropositivity across all infection categories. Although not statistically significant, these findings lay the groundwork for a comprehensive surveillance study on the Hepatitis B and Dengue viral infections in young adults. This study provides valuable insights into the prevalence patterns of Hepatitis B and Dengue virus, offering a basis for further research and public health interventions in this population.

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