Advances in the Application of Autologous Platelet Concentrate in the Field of Gynecology

Abstract

Autologous platelet concentrate (APC) is a platelet concentrate obtained by centrifugation of human or animal blood, mainly includes first-generation platelet concentrate platelet-rich plasma (PRP) and second-generation platelet concentrate platelet-rich fibrin (PRF), which is widely applied in varies fields such as dental implants, bone defect repairing and burn plastic surgery because of its role in wound healing and tissue repair. In recent years, autologous platelet concentrate has been applied to improve ovarian function, promote the repair of endometrial hyperplasia, treat cervical and vulvo-related lesions, and has achieved significant efficacy. However, there is a lack of effective integration of PRP and PRF research results in the field of gynecology. This paper systematically and comprehensively review the preparation, biological properties and applications in various gynecological diseases, in order to provide clinicians with new treatment ideas for gynecological diseases and reference for the further application of APC.

Keywords

• gynecologic diseases|platelet-rich plasma|platelet-rich fibrin|autologous platelet concentrates|endometrial hyperplasia|ovarian diseases|review