Frontiers in Neurology (Sep 2019)

Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases

  • Agnès Aghetti,
  • Agnès Aghetti,
  • Damien Sène,
  • Damien Sène,
  • Marc Polivka,
  • Natalia Shor,
  • Sarah Lechtman,
  • Sarah Lechtman,
  • Hugues Chabriat,
  • Hugues Chabriat,
  • Hugues Chabriat,
  • Eric Jouvent,
  • Eric Jouvent,
  • Eric Jouvent,
  • Stéphanie Guey,
  • Stéphanie Guey,
  • Stéphanie Guey

DOI
https://doi.org/10.3389/fneur.2019.00984
Journal volume & issue
Vol. 10

Abstract

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Cerebral amyloid angiopathy related inflammation (CAA-RI) is a rare form of CAA characterized by subacute encephalitic symptoms (cognitive decline, seizures, focal deficits) associated with extensive and confluent white matter lesions co-localizing with lobar microbleeds on brain MRI. We report two cases of unusual CAA-RI mimicking meningoencephalitis but without typical brain lesions on FLAIR and T2* sequences. These 2 cases may extend the clinical spectrum of CAA-RI by suggesting the possible occurrence of quite purely meningeal forms of CAA-RI.

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