Nature Communications (Jul 2017)

PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens

  • Erin C. Bush,
  • Forest Ray,
  • Mariano J. Alvarez,
  • Ronald Realubit,
  • Hai Li,
  • Charles Karan,
  • Andrea Califano,
  • Peter A. Sims

DOI
https://doi.org/10.1038/s41467-017-00136-z
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 7

Abstract

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Despite the importance of pharmacological and functional genomic screens the readouts are of low complexity. Here the authors introduce PLATE-Seq, a low-cost genome-wide mRNA profiling method to complement high-throughput screening.