Variation in auxin sensing guides AUX/IAA transcriptional repressor ubiquitylation and destruction

Martin Winkler; Michael Niemeyer; Antje Hellmuth; Philipp Janitza; Gideon Christ; Sophia L. Samodelov; Verona Wilde; Petra Majovsky; Marco Trujillo; Matias D. Zurbriggen; Wolfgang Hoehenwarter; Marcel Quint; Luz Irina A. Calderón Villalobos

doi:10.1038/ncomms15706

Nature Communications (Jun 2017)

Variation in auxin sensing guides AUX/IAA transcriptional repressor ubiquitylation and destruction

Martin Winkler,
Michael Niemeyer,
Antje Hellmuth,
Philipp Janitza,
Gideon Christ,
Sophia L. Samodelov,
Verona Wilde,
Petra Majovsky,
Marco Trujillo,
Matias D. Zurbriggen,
Wolfgang Hoehenwarter,
Marcel Quint,
Luz Irina A. Calderón Villalobos

Affiliations

Martin Winkler: Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry (IPB)
Michael Niemeyer: Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry (IPB)
Antje Hellmuth: Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry (IPB)
Philipp Janitza: Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg
Gideon Christ: Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry (IPB)
Sophia L. Samodelov: Institute of Synthetic Biology, University of Düsseldorf
Verona Wilde: Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry (IPB)
Petra Majovsky: Proteome Analytics Research Group, Leibniz Institute of Plant Biochemistry (IPB)
Marco Trujillo: Independent Junior Research Group Ubiquitination in Immunity, Leibniz Institute of Plant Biochemistry (IPB)
Matias D. Zurbriggen: Institute of Synthetic Biology, University of Düsseldorf
Wolfgang Hoehenwarter: Proteome Analytics Research Group, Leibniz Institute of Plant Biochemistry (IPB)
Marcel Quint: Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg
Luz Irina A. Calderón Villalobos: Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry (IPB)

DOI: https://doi.org/10.1038/ncomms15706
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 13

Abstract

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The phytohormone auxin is sensed by SCFTIR1-AUX/IAA receptors leading to AUX/IAA repressor ubiquitylation and turnover. Here the authors show that IAA6 and IAA19 differ in their ubiquitylation and turnover dynamics, differentially contributing to auxin sensing and enabling discrimination of auxin concentrations.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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