Nature Communications (Mar 2016)

Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer

  • Zhou Du,
  • Tong Sun,
  • Ezgi Hacisuleyman,
  • Teng Fei,
  • Xiaodong Wang,
  • Myles Brown,
  • John L. Rinn,
  • Mary Gwo-Shu Lee,
  • Yiwen Chen,
  • Philip W. Kantoff,
  • X. Shirley Liu

DOI
https://doi.org/10.1038/ncomms10982
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 10

Abstract

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Long non-coding RNAs (lncRNA; >200 base pair nucleic acids with little protein-coding capacity) are emerging as potentially important regulators of oncogenesis. Here the authors show tumour suppressive lncRNA sponge function for the protein products of prostate cancer driver genes.