Nature Communications (Jul 2021)

Pseudomonas aeruginosa PA14 produces R-bodies, extendable protein polymers with roles in host colonization and virulence

  • Bryan Wang,
  • Yu-Cheng Lin,
  • Alejandro Vasquez-Rifo,
  • Jeanyoung Jo,
  • Alexa Price-Whelan,
  • Shujuan Tao McDonald,
  • Lewis M. Brown,
  • Christian Sieben,
  • Lars E. P. Dietrich

DOI
https://doi.org/10.1038/s41467-021-24796-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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R-bodies are long, extendable protein polymers formed in the cytoplasm of some bacteria. Here, Wang et al. show that Pseudomonas aeruginosa produces R-bodies during colonization of plant and nematode hosts, and R-bodies induce ribosome cleavage and translational inhibition in nematodes.