Pregnancy management in a woman with inherited thrombophilia, personal history of preeclampsia and family history of eclampsias

Abstract

One of the most important aspects of reducing the incidence of preeclampsia is the most complete and timely assessment of risk factors for each patient. One of the well-known, but often overlooked, risk factors is a family history of preeclampsia. In the history of our patient during her first pregnancy the fact of her mother’s eclampsia was ignored, antithrombotic medication were not prescribed, and the pregnancy has ended in premature birth due to severe preeclampsia. The examination confirmed inherited thrombophilia – Leiden mutation. The next pregnancy was managed with appointment of antithrombotic medication – low molecular weight heparin and low doses of acetylsalicylic acid, without complications and ended in timely delivery.

Keywords

• preeclampsia
• thrombophilia
• leiden mutation
• acetylsalicylic acid
• low molecular weight heparin
• preterm birth