Does the A9285g Polymorphism in Collagen Type XII α1 Gene Associate with the Risk of Anterior Cruciate Ligament Ruptures?

K. Ficek; M. Stepien-Slodkowska; M. Kaczmarczyk; A. Maciejewska-Karlowska; M. Sawczuk; J. Cholewinski; A. Leonska-Duniec; A. Zarebska; P. Cieszczyk; P. Zmijewski

doi:10.2478/bjmg-2014-0022

Balkan Journal of Medical Genetics (Jun 2014)

Does the A9285g Polymorphism in Collagen Type XII α1 Gene Associate with the Risk of Anterior Cruciate Ligament Ruptures?

K. Ficek,
M. Stepien-Slodkowska,
M. Kaczmarczyk,
A. Maciejewska-Karlowska,
M. Sawczuk,
J. Cholewinski,
A. Leonska-Duniec,
A. Zarebska,
P. Cieszczyk,
P. Zmijewski

Affiliations

K. Ficek: Galen Orthopaedics, Bieruń, Poland
M. Stepien-Slodkowska: Department of Physical Culture and Health Promotion, University of Szczecin, Poland
M. Kaczmarczyk: Department of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland
A. Maciejewska-Karlowska: Department of Genetics, University of Szczecin, Szczecin, Poland
M. Sawczuk: Department of Genetics, University of Szczecin, Szczecin, Poland
J. Cholewinski: Galen Orthopaedics, Bieruń, Poland
A. Leonska-Duniec: Department of Physical Culture and Health Promotion, University of Szczecin, Poland
A. Zarebska: Department of Sport Education, Academy of Physical Education and Sport, Gdańsk, Poland
P. Cieszczyk: Department of Physical Culture and Health Promotion, University of Szczecin, Poland
P. Zmijewski: Department of Physiology, Institute of Sport, Warsaw, Poland Institute of Sport, Department of Physiology, Trylogii 2/16, 01-982 Warsaw, Poland. Tel.: +48-228340812. Fax: +480228350977.

DOI: https://doi.org/10.2478/bjmg-2014-0022
Journal volume & issue: Vol. 17, no. 1
pp. 41 – 46

Abstract

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One of the most severe injuries sustained by athletes is rupture of the anterior cruciate ligament (ACL). Recent investigations suggest that a predisposition for ACL rupture may be the result of specific genetic sequence variants. In light of this, we decided to investigate whether the COL12A1 A9285G polymorphism was associated with ACL ruptures in Polish football players.

Published in Balkan Journal of Medical Genetics

ISSN: 1311-0160 (Print); 2199-5761 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Science: Biology (General): Genetics
Website: https://sciendo.com/journal/BJMG

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