Diagnostics (May 2023)

Ultrahigh-Resolution Photon-Counting CT in Cadaveric Fracture Models: Spatial Frequency Is Not Everything

  • Theresa Sophie Patzer,
  • Andreas Steven Kunz,
  • Henner Huflage,
  • Nora Conrads,
  • Karsten Sebastian Luetkens,
  • Pauline Pannenbecker,
  • Mila Marie Paul,
  • Süleyman Ergün,
  • Thorsten Alexander Bley,
  • Jan-Peter Grunz

DOI
https://doi.org/10.3390/diagnostics13101677
Journal volume & issue
Vol. 13, no. 10
p. 1677

Abstract

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In this study, the impact of reconstruction sharpness on the visualization of the appendicular skeleton in ultrahigh-resolution (UHR) photon-counting detector (PCD) CT was investigated. Sixteen cadaveric extremities (eight fractured) were examined with a standardized 120 kVp scan protocol (CTDIvol 10 mGy). Images were reconstructed with the sharpest non-UHR kernel (Br76) and all available UHR kernels (Br80 to Br96). Seven radiologists evaluated image quality and fracture assessability. Interrater agreement was assessed with the intraclass correlation coefficient. For quantitative comparisons, signal-to-noise-ratios (SNRs) were calculated. Subjective image quality was best for Br84 (median 1, interquartile range 1–3; p ≤ 0.003). Regarding fracture assessability, no significant difference was ascertained between Br76, Br80 and Br84 (p > 0.999), with inferior ratings for all sharper kernels (p p p p > 0.999). Br76 and Br80 produced higher SNRs than all kernels sharper than Br84 (p ≤ 0.026). In conclusion, PCD-CT reconstructions with a moderate UHR kernel offer superior image quality for visualizing the appendicular skeleton. Fracture assessability benefits from sharp non-UHR and moderate UHR kernels, while ultra-sharp reconstructions incur augmented image noise.

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