Nature Communications (Sep 2018)

Augmentation of vaccine-induced humoral and cellular immunity by a physical radiofrequency adjuvant

  • Yan Cao,
  • Xiaoyue Zhu,
  • Md Nazir Hossen,
  • Prateek Kakar,
  • Yiwen Zhao,
  • Xinyuan Chen

DOI
https://doi.org/10.1038/s41467-018-06151-y
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 13

Abstract

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Vaccine adjuvants ensure sufficient engagement of the immune system in vaccination, however safety issues can be associated with novel chemical adjuvants. Here, Cao et al. report a physical radiofrequency adjuvant to simultaneously augment vaccine-induced humoral and cellular immune responses without potentially harmful adverse reactions.