E7 oncoprotein as a marker for persistence of human papillomavirus infection in patients with chronic cervicitis

Abstract

A comparative analysis of the results of clinical, gynecological and laboratory diagnostic methods of examination in 135 patients with chronic cervicitis. Patients were divided into 3 groups. Group 1 included 49 women with chronic cervicitis on the background of human papillomavirus types 16 and 18 in the cervical canal. In 12 patients of group I revealed the presence of E7 protein. Group 2 consisted of 32 patients with chronic cervicitis and human papillomavirus types 11 and 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 6 in the cervical canal. The group 3 included 54 patients with chronic cervicitis without the presence of human papillomavirus infection in the cervix.

Keywords

• hronic cervicitis
• human papilloma virus e7 oncoprotein colposcopy