Open Access Emergency Medicine (Jan 2022)
Emergency Decompression of Obstructive Uropathy Using Percutaneous Nephrostomy: Disease Pattern and Treatment Outcome at Two Urology Centers in Ethiopia
Abstract
Kaleab Habtemichael Gebreselassie,1 Fitsum Gebreegziabher Gebrehiwot,1 Haimanot Ewnetu Hailu,2 Andualem Deneke Beyene,3 Seid Mohammed Hassen,1 Ferid Ousman Mummed,1 Feysel Hassen Issack1 1Urology Unit, Department of Surgery, Saint Paul’s Hospital Millennium Medical College (SPHMMC), Addis Ababa, Ethiopia; 2Department of Public Health, Saint Paul’s Hospital Millennium Medical College (SPHMMC), Addis Ababa, Ethiopia; 3Department of Surgery, School of Medicine, College of Health Sciences, Addis Ababa University (AAU), Addis Ababa, EthiopiaCorrespondence: Kaleab Habtemichael GebreselassieDepartment of Surgery, Urology Unit, St. Paul’s Hospital Millennium Medical College, PO Box: 59004, Addis Ababa, EthiopiaTel +251-913632425Email [email protected]: Obstructive uropathy (OU) is a potentially life-threatening urologic emergency that requires urgent decompression. Percutaneous nephrostomy (PCN) is a commonly performed procedure to decompress OU. The objective of this study is to assess disease patterns and treatment outcome at two urologic centers in Ethiopia.Methods: A cross-sectional study was conducted on 110 patients who underwent emergency PCN from October 1, 2019 to September 30, 2020. Data were collected by a retrospective chart review. SPSS 25 was used for analysis. Descriptive statistics and logistic regression were utilized to assess disease pattern and significant predictors. A p-value of 80% of patients among which cervical cancer was the commonest (37.3%) followed by bladder cancer (17.3%). Acute kidney injury (AKI) accounted for 70% of the presenting indications for PCN. Success rate after emergency PCN was 75.5% and 41.8% of the cases developed post-procedure complications. Factors that predicted successful outcome include male gender [AOR = 5.72 (1.13– 28.92), 95% CI; p = 0.035], severe hydronephrosis pre-operatively [AOR = 7.12 (1.32– 38.45), 95% CI; p = 0.022], and use of combined imaging (ultrasound and fluoroscope) to guide PCN [AOR = 12.91 (1.13– 46.54), 95% CI; p = 0.039]. On the other hand, postoperative complication is a negative predictor [AOR = 0.26 (0.08– 0.86), 95% CI; p = 0.027].Conclusion: In this study, overall success of emergency PCN is low. Presence of severe hydronephrosis predicts technical ease and better outcome of PCN. Procedures performed under ultrasound and fluoroscope guidance also improve outcome. Postoperative complication rate is high in this study and mandates strict preventive measures as it predicts unfavorable outcome.Keywords: obstructive uropathy, percutaneous nephrostomy, emergency decompression, Ethiopia