BMC Medical Research Methodology (Jan 2023)

Minimizing population health loss due to scarcity in OR capacity: validation of quality of life input

  • Benjamin Y. Gravesteijn,
  • Kira S. van Hof,
  • Eline Krijkamp,
  • Franck Asselman,
  • C. René Leemans,
  • Anouk M.I.A. van Alphen,
  • Henriëtte van der Horst,
  • Guy Widdershoven,
  • Leonie Baatenburg de Jong,
  • Hester Lingsma,
  • Jan Busschbach,
  • Rob Baatenburg de Jong

DOI
https://doi.org/10.1186/s12874-022-01818-z
Journal volume & issue
Vol. 23, no. 1
pp. 1 – 9

Abstract

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Abstract Objectives A previously developed decision model to prioritize surgical procedures in times of scarce surgical capacity used quality of life (QoL) primarily derived from experts in one center. These estimates are key input of the model, and might be more context-dependent than the other input parameters (age, survival). The aim of this study was to validate our model by replicating these QoL estimates. Methods The original study estimated QoL of patients in need of commonly performed procedures in live expert-panel meetings. This study replicated this procedure using a web-based Delphi approach in a different hospital. The new QoL scores were compared with the original scores using mixed effects linear regression. The ranking of surgical procedures based on combined QoL values from the validation and original study was compared to the ranking based solely on the original QoL values. Results The overall mean difference in QoL estimates between the validation study and the original study was − 0.11 (95% CI: -0.12 - -0.10). The model output (DALY/month delay) based on QoL data from both studies was similar to the model output based on the original data only: The Spearman’s correlation coefficient between the ranking of all procedures before and after including the new QoL estimates was 0.988. Discussion Even though the new QoL estimates were systematically lower than the values from the original study, the ranking for urgency based on health loss per unit of time delay of procedures was consistent. This underscores the robustness and generalizability of the decision model for prioritization of surgical procedures.

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