The parasitic infection is an affection of the body as well as the eye with parasites, protozoa's, worms and ectoparasites, with world incidence of 30%. These diseases are chronic, systemic diseases because of weak innate immunity and ability of parasites to evade immune answer of the host or increasing the resistance to the adaptive immunity of the host. Parasites can evade immunity of the host by: antigens variations, forming cysts, changing the hosts and by synthesis of some cytokines, which decrease immunity of the host. Ascaris lumbricoides is the largest intestinal nematode parasitizing man. The worm is known to cause subconjunctival mass, granulomatous iridocyclitis, choroiditis, recurrent vitreous hemorrhage, chronic dacryocystitis and invasion into the subretinal space. The goal of this case was to analyze the affection of the eye, caused by the Ascaris lumbricoides as very rare ocular pathology.