Case Report: Unusual Cause of Fever in Ulcerative Colitis Treated with Infliximab

Abstract

Sumei Sha,1,* Haitao Shi,1,* Jie Wu,2,* Ming Zhang,3 Bin Qin,1 Longbao Yang,1 Xin Liu1 1Department of Gastroenterology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 2Department of Pathology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China; 3Department of Respiratory, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Liu, Department of Gastroenterology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, 710004, People’s Republic of China, Email [email protected]: Patients with inflammatory bowel disease are at high risk for opportunistic infections, and fungal infections are relatively uncommon among various infections.Case: This case is the first reported ulcerative colitis accompanied with Cryptococcus neoformans infection after infliximab treatment. In the course of the disease, the patients had a variety of opportunistic infections, including viruses, fungi and bacteria.Conclusion: This case highlights the importance of paying continued attention to opportunistic infections for patients with inflammatory bowel disease.Keywords: ulcerative colitis, Cryptococcus neoformans pneumonia, cytomegalovirus infection, clostridium difficile infection, biological agents, case report

Keywords

• ulcerative colitis
• cryptococcus neoformans pneumonia
• cytomegalovirus infection
• clostridium difficile infection
• biological agents
• case report