Acta Biomedica Scientifica (Nov 2014)

ACTIVITY OF AMINOLEVULINATE SYNTHASE OF BONE MARROW AND LIVER OF NEWBORN AUGUST AND WISTAR RATS AFTER ACUTE POSTNATAL HYPOXIA

  • L. I. Kolesnikova,
  • A. S. Popova,
  • L. I. Krupitskaya,
  • A. I. Sinitskiy

Journal volume & issue
Vol. 0, no. 6
pp. 60 – 62

Abstract

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Newborn Wistar and August rats (20 rats in each experimental group) were exposed to acute postnatal hypoxic hypoxia (by the mixture of 95% nitrogen and 5% oxygen). Determination of activity of aminolevulinate synthase (ALA-synthase) in bone marrow and liver were in control group, and on the 1st and 3rd days of life (in liver - only on the 3rd day). Infant rats of various lines differed by the response of an organism to hypoxic exposure that confirms its genetic predetermination. Activities of ALA-synthase in bone marrow and liver were reciprocal both in normal development and after hypoxia. K

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