Communications Medicine (Dec 2021)

Adherence and sustainability of interventions informing optimal control against the COVID-19 pandemic

  • Laura Di Domenico,
  • Chiara E. Sabbatini,
  • Pierre-Yves Boëlle,
  • Chiara Poletto,
  • Pascal Crépey,
  • Juliette Paireau,
  • Simon Cauchemez,
  • François Beck,
  • Harold Noel,
  • Daniel Lévy-Bruhl,
  • Vittoria Colizza

Journal volume & issue
Vol. 1, no. 1
pp. 1 – 13


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Di Domenico and Sabbatini et al. model the impact of lockdowns of varying duration and intensity on the control of COVID-19, using data from the third wave of the epidemic in the Paris region of France. The authors introduce a measure of policy-induced fatigue, the ‘distress index’, that helps to explain why shorter, more stringent restrictions might be more effective.