mSphere of Influence: a Community To Study Communities

Abstract

ABSTRACT Dominique Limoli studies polymicrobial interactions during cystic fibrosis respiratory disease. In this mSphere of Influence article, she reflects on how two papers (D. A. Hogan, S. D. Willger, E. L. Dolben, T. H. Hampton, et al., PLoS One 11:e0149998, 2016, https://doi.org/10.1371/journal.pone.0149998, and P. Jorth, B. J. Staudinger, X. Wu, K. B. Hisert, et al., Cell Host & Microbe 18:307–319, 2015, https://doi.org/10.1016/j.chom.2015.07.006) have influenced her thinking and research direction, which aims to understand interspecies bacterial communication during airway infections. These studies highlighted for her a need for new perspectives on the pathology of chronic infections in order to improve interventions.

Keywords

• Pseudomonas aeruginosa
• cystic fibrosis
• lung infection
• microbial communities