Hydrogen Sulfide, Oxidative Stress and Periodontal Diseases: A Concise Review
Maria Greabu,
Alexandra Totan,
Daniela Miricescu,
Radu Radulescu,
Justina Virlan,
Bogdan Calenic
Affiliations
Maria Greabu
Dental Medicine Faculty, Biochemistry Department, University of Medicine and Pharmacy CAROL DAVILA, 8 Blvd EroilorSanitari, sect.5, 050474 Bucharest, Romania
Alexandra Totan
Dental Medicine Faculty, Biochemistry Department, University of Medicine and Pharmacy CAROL DAVILA, 8 Blvd EroilorSanitari, sect.5, 050474 Bucharest, Romania
Daniela Miricescu
Dental Medicine Faculty, Biochemistry Department, University of Medicine and Pharmacy CAROL DAVILA, 8 Blvd EroilorSanitari, sect.5, 050474 Bucharest, Romania
Radu Radulescu
Dental Medicine Faculty, Biochemistry Department, University of Medicine and Pharmacy CAROL DAVILA, 8 Blvd EroilorSanitari, sect.5, 050474 Bucharest, Romania
Justina Virlan
Dental Medicine Faculty, Biochemistry Department, University of Medicine and Pharmacy CAROL DAVILA, 8 Blvd EroilorSanitari, sect.5, 050474 Bucharest, Romania
Bogdan Calenic
Dental Medicine Faculty, Biochemistry Department, University of Medicine and Pharmacy CAROL DAVILA, 8 Blvd EroilorSanitari, sect.5, 050474 Bucharest, Romania
In the past years, biomedical research has recognized hydrogen sulfide (H2S) not only as an environmental pollutant but also, along with nitric oxide and carbon monoxide, as an important biological gastransmitter with paramount roles in health and disease. Current research focuses on several aspects of H2S biology such as the biochemical pathways that generate the compound and its functions in human pathology or drug synthesis that block or stimulate its biosynthesis. The present work addresses the knowledge we have to date on H2S production and its biological roles in the general human environment with a special focus on the oral cavity and its involvement in the initiation and development of periodontal diseases.
