Heat inactivation of the severe acute respiratory syndrome coronavirus 2

Christophe Batéjat; Quentin Grassin; Jean-Claude Manuguerra; India Leclercq

Journal of Biosafety and Biosecurity (Jun 2021)

Heat inactivation of the severe acute respiratory syndrome coronavirus 2

Christophe Batéjat,
Quentin Grassin,
Jean-Claude Manuguerra,
India Leclercq

Affiliations

Christophe Batéjat: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence (CIBU), 28 rue du Dr. Roux, Paris, France
Quentin Grassin: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence (CIBU), 28 rue du Dr. Roux, Paris, France
Jean-Claude Manuguerra: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence (CIBU), 28 rue du Dr. Roux, Paris, France
India Leclercq: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence (CIBU), 28 rue du Dr. Roux, Paris, France; Université de Paris, Cellule Pasteur, 28 rue du Dr. Roux F-75015 Paris, France; Corresponding author at: Université de Paris, Cellule Pasteur, 28 rue du Dr. Roux F-75015 Paris, France.

Journal volume & issue: Vol. 3, no. 1
pp. 1 – 3

Abstract

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Cell culture medium, nasopharyngeal and sera samples spiked with SARS-CoV-2 were subjected to heat inactivation for various periods of time, ranging from 30 s to 60 min. Our results showed that SARS-CoV-2 could be inactivated in less than 30 min, 15 min, and 3 min at 56 °C, 65 °C, and 95 °C, respectively. These data could help laboratory workers to improve their protocols by handling the virus in biosafety conditions.

Published in Journal of Biosafety and Biosecurity

ISSN: 2588-9338 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Science: Biology (General)
Website: https://www.keaipublishing.com/en/journals/journal-of-biosafety-and-biosecurity/

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