Single-molecule insights into surface-mediated homochirality in hierarchical peptide assembly

Yumin Chen; Ke Deng; Shengbin Lei; Rong Yang; Tong Li; Yuantong Gu; Yanlian Yang; Xiaohui Qiu; Chen Wang

doi:10.1038/s41467-018-05218-0

Nature Communications (Jul 2018)

Single-molecule insights into surface-mediated homochirality in hierarchical peptide assembly

Yumin Chen,
Ke Deng,
Shengbin Lei,
Rong Yang,
Tong Li,
Yuantong Gu,
Yanlian Yang,
Xiaohui Qiu,
Chen Wang

Affiliations

Yumin Chen: CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, China
Ke Deng: CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, China
Shengbin Lei: Department of Chemistry, School of Science & Collaborative Innovation Center of Chemistry Science and Engineering (Tianjin), Tianjin University
Rong Yang: CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, China
Tong Li: School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology
Yuantong Gu: School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology
Yanlian Yang: CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, China
Xiaohui Qiu: CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, China
Chen Wang: CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, China

DOI: https://doi.org/10.1038/s41467-018-05218-0
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 8

Abstract

Read online

Most chiral molecules and structures in living organisms exist as single enantiomers, but why? Here, the authors investigated surface-mediated homochirality on the single-molecule level and show that it can be triggered by the chirality unbalance of two adsorption configuration monomers.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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